Cephalosporins classification:

Cephalosporins classification:

• I generation - parenteral: Cefazolin, oral: Cefalexin, Cefadroxil. Active against Streptococcusspp. (S.pyogenes, S.pneumoniae) and methicillin resistant Staphylococcus spp.
• II generation parenteral: Cefuroxime, oral: Cefuroxime axetil, Cefaclor. Active against Streptococcusspp., Staphylococcus spp, Neisseriaspp., E.coli, Shigellaspp., Salmonellaspp., P.mirabilis, Klebsiellaspp., P.vulgaris, C.diversus
• III generation parenteral: Cefotaxime, Ceftriaxone, Ceftazidime, Cefoperazone, Cefoperazone/Sulbactam, oral: Cefixime, Ceftibuten. Active against Streptococcus spp., S.aureu, exceptMRSA,meningococci, gonococci, H.influenzae, M.catarrhalis, Enterobacteriaceae
• IV generation parenteral: Cefepime. Active against Enterobacter spp., C.freundii, Serratiaspp., M.morganii,P.stuartii, P.rettgeri.
• V generation: Ceftobiprole, Ceftaroline
  
  Reference: J Am Pharm Assoc, Pharmacists Association: