Clinical Features in Patients with Wilson Disease
Hepatic
· Asymptomatic hepatomegaly
· Isolated splenomegaly
· Persistently elevated serum aminotransferase activity (AST, ALT)
· Fatty liver
· Acute hepatitis
· Resembling autoimmune hepatitis
· Cirrhosis: compensated or decompensated
· Acute liver failure
Neurological
· Movement disorders (tremor, involuntary movements)
· Drooling, dysarthria
· Rigid dystonia
· Pseudobulbar palsy
· Dysautonomia
· Migraine headaches
· Insomnia
· Seizures
Psychiatric
· Depression
· Neurotic behaviours
· Personality changes
· Psychosis
Other Systems
· Ocular: Kayser-Fleischer rings, sunflower cataracts
· Cutaneous: lunulae ceruleae
· Renal abnormalities: aminoaciduria and nephrolithiasis
· Skeletal abnormalities: premature osteoporosis and arthritis
· Cardiomyopathy, dysrhythmias
· Pancreatitis
· Hypoparathyroidism
· Menstrual irregularities; infertility, repeated miscarriages
Image Courtesy: www.eurowilson.org
Text Reference: http://www.wilsonsdisease.org
· Asymptomatic hepatomegaly
· Isolated splenomegaly
· Persistently elevated serum aminotransferase activity (AST, ALT)
· Fatty liver
· Acute hepatitis
· Resembling autoimmune hepatitis
· Cirrhosis: compensated or decompensated
· Acute liver failure
Neurological
· Movement disorders (tremor, involuntary movements)
· Drooling, dysarthria
· Rigid dystonia
· Pseudobulbar palsy
· Dysautonomia
· Migraine headaches
· Insomnia
· Seizures
Psychiatric
· Depression
· Neurotic behaviours
· Personality changes
· Psychosis
Other Systems
· Ocular: Kayser-Fleischer rings, sunflower cataracts
· Cutaneous: lunulae ceruleae
· Renal abnormalities: aminoaciduria and nephrolithiasis
· Skeletal abnormalities: premature osteoporosis and arthritis
· Cardiomyopathy, dysrhythmias
· Pancreatitis
· Hypoparathyroidism
· Menstrual irregularities; infertility, repeated miscarriages
Image Courtesy: www.eurowilson.org
Text Reference: http://www.wilsonsdisease.org
ReplyDeleteHello Am From The UK , I want to write a little testimony about the good work of doctor Oyagu who cured me from Hsv 1 and 2 for just 2 weeks with his herbal medicine, I never believe I can be normal again and have a good life like others I always regretted the day I got diagnose with the virus, I was lost of hope when my doctor told me there is no cure for it but I keep thinking and thinking about my future, if I can have kids of my own well I am so grateful for my helper who get me cured with his herbal medicine, I go online in search of anything that can help me because I can’t deal with it forever so I found this doc Oyagu email on a blog of someone who was cured by him I quickly contact him for help and explain all my pain to him, he told me not to worry about it there is cure for real, I never believe until he send me the herbal medicine when I order for it and I have it within 4 days that is how I took the medicine for 2 week and the following week I go for test just to confirm I was 100% cured from this sickness what a miracle in my life I am so happy right now, you can also get in contact with him if you have such sickness through email address oyaguherbalhome@gmail. com or text him on what's app, phone number +2348101755322 Dr Oyagu also has remedy to others disease like COLD SORES,HIV/AIDS,DIABETES.CANCER,HIGH BLOOD PRESSURE AND MANY MORE. I oblige everyone to contact this powerful herbalist Dr Oyagu and be free from suffering.